Selected Reference for Oral Systemic Articles
Costerton J, Keller D. Oral periopathogens and systemic effects. Gen Dent. 2007 May-June;55(3):210-15.
Geerts SO et al. Systemic release of endotoxins induced by gentle mastication: association with periodontitis severity. J Periodontol. 2002 Jan;73(1):73-78.
Cardiovascular Disease
Angeli F et al. Association between periodontal disease and left ventricle mass in essential hypertension. Hypertension. 2003 Mar;41(3):488-92.
D’Aiuto F et al. Periodontal infections cause changes in traditional and novel cardiovascular risk factors: results from a randomized controlled clinical trial. Am Heart J. 2006 May;151(5):977-84.
Deshpande RG et al. Invasion of Aortic and Heart Endothelial Cells by Porphyromonas gingivalis. Infect Immun. 1998 Nov.; 66(11): 5337–43.
Desvarieux M et al. Periodontal microbiota and carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology Study. Circulation. 2005 Feb 8;111(5):576-82.
Ford PJ et al. Cardiovascular and oral disease interactions: what is the evidence? Prim Dent Care. 2007 Apr;14(2):59-66.
Furuichi Y et al. Associations of periodontal status with general health conditions and serum antibody titers for Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans. J Periodontol. 2003 Oct;74(10):1491-97.
Gibson FC 3rd et al. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E--deficient mice. Circulation. 2004 June 8;109(22):2801-6.
Golebiewska M et al. Periodontal condition in patients with cardiovascular diseases. Adv Med Sci. 2006;51 Suppl 1:69-72.
Inoue K et al. Association of periodontitis with increased white blood cell count and blood pressure. I. 2005;14(6):383; author reply 384.
Jain A et al. Role for periodontitis in the progression of lipid deposition in an animal model. Infect Immun. 2003 Oct;71(10):6012-8.
Kozarov EV, et al. Human atherosclerotic plaque contains viable invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Arterioscler Thromb Vasc Biol. 2005 Mar;25(3):E17-8.
Kuramitsu HK et al. Interactions of Porphyromonas gingivalis with host cells: implications for cardiovascular diseases. J Periodontol. 2003 Jan;74(1):85-9.
Kuramitsu HK et al. Role of periodontal bacteria in cardiovascular disease. Ann Periodontol. 2001 Dec;6(1)41-7.
Maiborodin IV et al. Changes in gum in cases of arterial hypertension combination with periodontitis. Stomatologiia (Mosk). 2005:84(6):15-19.
Diabetes
Arnush M et al. IL-1 produced and released endogenously within human islets inhibits beta cell function. J Clin Invest. 1998 Aug 1;102(3):516-26.
Engebretson S et al. Plasma levels of tumour necrosis factor-a in patients with chronic periodontitis and type 2 diabetes. J Clin Periodontol. 2007 Jan;34(1):18-24. Epub 2006 Nov 20.
Grossi, SG. Treatment of periodontal disease and control of diabetes: an assessment of the evidence and need for future research. Ann Periodontol. 2001 Dec;6(1):138-45.
Hotamisligil GS et al. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest. 1995 May;95(5):2409-15.
Iacopino AM et al. Periodontitis and diabetes interrelationships: role of inflammation..Ann Periodontol 2001 Dec;6(1);125-37.
Iwamoto Y, et al. The effects of antimicrobial periodontal treatment on circulating tumor necrosis factor-alpha and glycated hemoglobin level in patients with type 2 diabetes. J Periodontol. 2001 Jun;72(6);774-8.
Kesavalu L et al. In vivo induction of proinflammatory cytokines in mouse tissue by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2002 Jun;17(3):177-80.
Pischon N. et al. Obesity, Inflammation and Periodontal Disease J Dent Res. 2007 May;86(5);400-9.
Schara R et al. Periodontal disease and diabetes metabolic control: a full-mouth disinfection approach. J Int Acad Periodontol. 2006 Apr;8(2):61-6.
Pregnancy
Barak, S et al. Evidence of periopathogenic microorganisms in placentas of women with preeclampsia. J Periodontol. 2007 Apr;78(4):670-6.
MacDonald AB. Alzheimer’s neuroborreliosis with trans-synaptic spread of infection and neurofibrillary tangles derived from intraneuronal spirochetes. Med Hypothesis. 2007;68(4):822-5.