How the Perio Tray™ Works

The whole Perio Protect Method™ comes down to one small, custom-fitted tray. It delivers prescription medication to the exact places brushing, rinsing and flossing can’t reach — to treat gum disease, ease tooth sensitivity, and more — in just minutes a day, from the comfort of home.

D2 Jenny Bathroom-1451
The Perio Trays® by Perio Protect.

The Perio Tray™

FDA-cleared. Patented seal. One custom-fitted
tray that works with all our gels.

WHAT IS THE PERIO TRAY?

A custom-fitted tray that does what a toothbrush can’t

The Perio Tray™ looks a little like a clear retainer or mouthguard — but it’s doing something a retainer never could. Each tray is custom-made for your mouth from impressions or scans of your teeth, with an internal seal that’s the heart of the whole design.

That seal lets the tray carry prescription gel exactly where it’s needed — deep below the gum line and held against the surface of your teeth — and keep it there long enough to work. Ordinary brushing, rinsing and flossing simply can’t do that, which is why some problems keep coming back.

It’s the only customized periodontal medicament carrier with FDA clearance and years of research behind it — and it’s the foundation for everything Perio Protect does. Depending on your needs, the same tray pairs with different prescription gels to treat gum disease, relieve tooth sensitivity, and more.

FDA-Cleared
Patented Seal
Non-Invasive

Why the Tray Reaches What Brushing Can’t

The problems the tray treats live where everyday brushing, rinsing and flossing can’t reach. Here’s the simple reason ordinary homecare falls short — and how the tray changes that.

Bacteria thrive deep below the gum line in the periodontal pocket.

The trouble hides deep in pockets

Whether it’s bacteria deep in the pockets below your gums or worn, sensitive spots on your teeth, the trouble sits where a toothbrush simply can’t get to it.

Brushing, rinsing and flossing cannot reach the bacteria.

Brushing and flossing fail to reach

Brushing, rinsing and flossing are important. But these efforts fail to reach deep below the gum line where bacteria thrive—in the periodontal pockets.

The Perio Tray® delivers medicine into the periodontal pockets and holds it there.

The tray places medicine at the source

Your custom tray and its patented seal carry prescription gel straight to the source, below the gum line or against the tooth surface, wherever it’s needed.

Which Sounds Like You?

The same custom tray treats more than one problem — it just depends on the prescription gel your dentist pairs with it.

GUM DISEASE

Bleeding, swollen, or receding gums

Paired with PerioGel®, the tray carries medication deep below the gum line to fight the bacteria behind gingivitis and periodontitis — where brushing and flossing can’t reach. Whiter teeth and fresher breath come along for the ride.

TOOTH SENSITIVITY

Wincing at cold, sweets, or brushing

Paired with ReminGel™, the tray seals enamel-building minerals against your teeth — rebuilding the surface and easing sensitivity for good, instead of just masking the pain. Fluoride-free and safe for daily use.

Same tray, different gel. Many patients use both—one custom fit covers it.

How Treatment Works, Start to Finish

Getting started is simpler than most people expect. Three steps, then just minutes a day.

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1

Talk to your dentist

Ask your dentist about Perio Protect, or find a provider near you. They’ll confirm whether the Perio Tray is right for your gums.

Jenny with trays and instructions

2

Get your custom trays

Your dentist takes impressions or scans of your mouth. Our St. Louis lab uses them to build trays fitted precisely to you.

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3

Treat at home, daily

Place a small amount of your prescribed gel in each tray and wear it for just 10–15 minutes a day — while you shower, watch TV, or get ready.

Your dentist designs a plan specific to you, and adjusts it over time. Once your gums reach the results you’re after, treatment shifts to simple maintenance to keep them there.

Meet the Prescription Gels

Each gel is formulated for a specific job and works with the same custom tray. Here’s a closer look at what your dentist can prescribe.

GUM DISEASE

ReminGel (300 x 137 px) (3)
ReminGel (300 x 137 px) (4)

Prescription Gum Disease Treatment

Hydrogen peroxide-based gel that breaks down harmful bacteria below the gum line. Combats gingivitis and periodontitis where brushing and flossing can’t reach.

1.7% hydrogen peroxide
Reduces bacteria & bleeding
Whitens teeth as a side benefit
Soft mint flavor
Also available as PerioGelX with Xylitol

TOOTH SENSITIVITY

ReminGel (300 x 137 px) (600 x 200 px) (1)

Tooth Sensitivity & Enamel Repair

Hydroxyapatite-based gel that doesn’t just mask sensitivity — it repairs and rebuilds your tooth’s natural structure. Fluoride-free and safe for long-term daily use.

Hydroxyapatite rebuilds enamel
Fills exposed dentin tubules
Reduces white spot lesions
Quick 3–15 minute sessions
Safe for children and adults

Gum Disease Doesn’t Stay in Your Mouth

Studies have linked the bacteria that cause gum disease to systemic inflammation and
serious health conditions. Treating your gums is about more than your smile.

Heart Disease
Type 2 Diabetes
Respiratory Disease
Alzheimer’s Disease
Colorectal Cancer
Pre-term & Low Birth-Weight Babies
Dr. Duane Keller, DMD

"When we were ready to start the second surgery, she said, 'that's not gonna happen.'"

Dr. Duane Keller

Dentist & Founder of Perio Protect

WHERE THE TRAY CAME FROM

It started with a dentist, his mother, and a better idea

Dr. Duane Keller treated his mother’s gum disease the traditional way — surgery. It worked. But when it came time for a second round, she refused to go through it again.

So he set out to solve the real problem: how do you get medication to an infection deep below the gums without the pain? After many iterations, he invented the patented Perio Tray — and a gentler way to treat gum disease was born.

Today, tens of thousands of Perio Trays ship from our St. Louis lab to patients across the country every year. Read the full story →

What Patients Are Saying

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“My teeth are definitely whiter, my gums don’t bleed like they used to, and at my last cleaning my hygienist told me my deep pockets went from 6s down to 3s!”

Amber M.

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“The trays are easy to use and have become part of my daily routine. I really didn’t expect to see results this fast — I’m truly glad I tried it.”

Germaine R.

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“I’ve had gum disease for years, but my gums are now healthier than they’ve been in a long time. Perio Protect has been key.”

Paul T.

Is the Perio Tray™ Right for You?

If you have gum disease, bleeding gums, or you’re working to keep crowns and implants healthy, the Perio Tray™ may be a good fit. The best way to know is to ask a provider.