PerioGel™ – Prescription Gum Disease Treatment
Gum Disease
Treatment Gel
PerioGel™ is more than a gum treatment — it helps restore gum health deep below the surface.
PerioGel is designed to help reduce the harmful bacteria that contribute to gum disease, supporting healthier gums and improved oral health. Used with custom trays, it delivers medication deep beneath the gumline where brushing and flossing alone can’t reach, providing targeted care where it’s needed most.
47%
of American adults have
chronic periodontal disease
Traditional Gum Disease Treatment Was Built to Repeat, Not Resolve
For decades, the standard approach has been scaling and root planing combined with antibiotics. It’s uncomfortable, it’s temporary, and it’s typically repeated every 3 months.
That cycle manages symptoms without addressing the ongoing bacterial infection between office visits. The result? Nearly half of American adults still live with chronic gum disease.
PerioGel and the Perio Tray were designed for a different outcome — a minimally invasive, at-home treatment that works every day to keep bacteria in check and support lasting gum health.
Based on peer-reviewed studies in the American Journal of Dentistry and the Journal of Clinical Dentistry
What is PerioGel?
PerioGel™ is our non-invasive prescription hydrogen peroxide-based gel that works with custom-fit dental trays to combat gum disease by breaking down the cell walls of bacteria causing infections and oral wounds associated with gum disease like gingivitis and periodontitis. The patented seal system delivers medication deep into the pockets between the teeth and gums where brushing and flossing can't reach. It also promotes whiter teeth!
How PerioGel Works
A simple and non-invasive treatment for gum disease
Perio Protect is a comprehensive approach to gum disease treatment. The approach combines dental cleanings with the comfortable Perio Tray® delivery of medication that patients use at home between office visits.
- Your dentist or hygienist will take measurement of your mouth and send them to the dental laboratory along with a mold of your mouth.
- The lab will use these measurements to customize an internal seal for each Perio Tray.
- When the tray is ready, patients put medication directly in the Tray and wear it for several minutes each day.
Clinical studies show the Perio Tray method reduces bacteria, decreases bleeding, lowers inflammation markers, and reduces pocket depths.
Learn more about how the Perio Tray® works to deliver medicine deep into perio pockets →
Why Patients Choose PerioGel to Treat Gum Disease
A Non-Invasive Option That Works
Our goal is to help patients avoid repetitive scaling and surgery when possible. Patients are empowered to care for themselves daily—beyond brushing and flossing.
Healthier Gums, Healthier You
Gum disease doesn't stay in your mouth. The bacteria that cause periodontal infection can impact your overall health — from heart disease to diabetes complications. Treating your gums isn't just about your smile; it's about your whole-body wellness.
Fresher Breath & White Teeth
By drastically reducing bacteria, Perio Protect also freshens your breath. In addition, the same antimicrobials that treat gum disease also happen to deliver prescription-strength whitening benefits.
Comfortable & Convenient
Treatment takes just 10–15 minutes a day, and you wear the trays while you go about your life — mow the lawn, take a shower, make your morning commute. No office visits, no downtime, no disruption to your routine.
Frequently Asked Questions
PerioProtect Trays are custom-fitted dental trays designed for at-home treatment of gum disease. PerioGel is our prescription hydrogen peroxide-based gel that works with the trays to combat gum disease by breaking down harmful bacteria below the gum line. The patented seal system delivers medication where brushing and flossing can't reach.
Patient Testimonials
"I’ve been using PerioProtect for about a month, and I’m honestly impressed. My teeth are definitely whiter, my gums don’t bleed like they used to, and at my last cleaning my hygienist told me my deep pockets went from 6s down to 3s!"
Amber M.
"I’ve been using the periodontal kit for 2 1/2 weeks, once a day, and I really see results in breath freshness, teeth are whiter and gums are stronger with less sensitivity and bleeding with the flossing process."
Germaine R.
"As a Dental Hygienist, I love this product. It works because of the science behind hydrogen peroxide, bacterial cell destruction and a custom fabricated tray. Well worth the cost!"
Sandra M.
PerioGel Videos
Learn More About PerioProtect Trays
Discover how PerioProtect Trays work—and why dentists trust them above all others for at-home dental care.
PerioProtect Trays are the #1 prescribed, FDA-cleared system for delivering prescription-strength therapy safely and comfortably in your own home. Learn how this tray-based approach helps target gum bacteria, support healthier gums, and protect your teeth.
Hear from the Founder
Dr. Duane Keller didn't set out to build a company — he set out to help his mother avoid another gum surgery.
After her first procedure left her with gaps, sensitivity, and pain, he began searching for a better way. When small brushes, medicated floss, and injections all fell short, that search led to the creation of the Perio Tray — a device designed to deliver medicine directly beneath the gums.
Redondo Beach Dental Loves PerioGel
Hear how Dr. Michael Fulbright uses Perio Protect to improve patient outcomes — from gingivitis to periodontitis.
The Perio Tray delivers 1.7% hydrogen peroxide gel directly below the gum line, and patients appreciate how simple it is to use. Dr. Fulbright incorporates tray therapy into his treatment protocols for lasting results between office visits.
What About Cost and Insurance?
We understand that cost is an important consideration when choosing any dental treatment. Here's what you need to know:
Insurance Coverage
Coverage varies by plan, so we recommend checking with your insurance provider or asking your dental office to verify benefits. Many HSA or FSA plans can be used towards benefits.
Payment
Most PerioProtect providers offer flexible payment plans or financing options to make treatment accessible. Don't let cost concerns prevent you from getting relief—talk to your provider about what options are available.
Questions about coverage?
Your dental office can help verify your insurance benefits and provide a treatment estimate before you begin.
